SHBG: A Small Protein With a Big Job

Quick take:
SHBG is a protein your liver makes. It carries sex hormones (testosterone and estrogen) in your blood and helps control how much “free” (active) hormone your body can use.

Why you should care

  • Low SHBG often shows up with insulin resistance and belly/visceral fat.
  • When SHBG is low, you can have more “free” hormones floating around, which can throw things off.

What tends to raise SHBG

  • Better insulin sensitivity: When insulin comes down, SHBG usually goes up.
    • How to help: move daily, lift weights, walk after meals, get good sleep.
    • Metformin (if your provider recommends it) can improve insulin sensitivity.
  • Healthy weight around the waist: Less visceral (belly) fat → higher SHBG.
  • Thyroid support: T3 thyroid hormone signals the liver to make more SHBG. (If thyroid is low, SHBG can be low, too.)

What tends to lower SHBG

  • Central/visceral fat (weight carried around the middle).
  • High-carb eating patterns, especially lots of refined carbs and sugar (often paired with weight gain and higher insulin).

Simple action plan

  • Protein + fiber at most meals (think lean meats, eggs, Greek yogurt, beans, veggies).
  • Cut back on refined carbs (sugary drinks, sweets, white breads).
  • Move more (aim for daily steps + 2–3 days of strength training).
  • Sleep 7–9 hours to help insulin.
  • Ask your provider about metformin if insulin resistance is an issue and check thyroid labs if SHBG seems off.

Bottom line:
Treat SHBG like a dashboard light. If it’s low, look under the hood—insulin, waist size, and thyroid often explain why. Fix those, and SHBG usually moves in the right direction.

Tasha Vallee, Vallee Health Repair, Illinois

Posted in